AASLD The Liver Meeting® 2020: Antaros Medical presents data on non-invasive MRI prediction of MASH and advanced liver fibrosis in patients with MASLD

Antaros Medical, in collaboration with Boehringer Ingelheim and Uppsala University, are presenting brand new data from our liver imaging method study AM-02 at this year’s AASLD TLMdX. The data is giving novel insights on the value of Magnetic Resonance Imaging (MRI) in metabolic dysfunction-associated steatotic liver disease (MASLD; previously called non-alcoholic fatty liver disease or NAFLD).

MASLD affects around 25-30% of the adult population worldwide. The disease is associated with an increased risk of advanced fibrosis, cirrhosis, and liver-related mortality. It is crucial to understand disease progression and severity for both clinical management and clinical research. Today, liver biopsy is used for disease stratification but is limited by cost and risks. MRI biomarkers have emerged as key non-invasive alternatives to accurately detect hepatic steatosis and liver fibrosis and could potentially also be used to identify the progressive form of metabolic dysfunction-associated steatohepatitis (MASH; previously called non-alcoholic steatohepatitis or NASH).

The results from our liver imaging method study further underline the value of MRI in MASLD. They show that MR-based biomarkers predict both MASH and advanced fibrosis in this patient population. To read more about our results, visit the following posters/abstracts presented at this year’s AASLD the Liver Meeting (TLMdX).

Bivariate MR Imaging biomarker to improve prediction of advanced fibrosis in subjects with biopsy proven MASLD

Authors: P Hockings, E Johansson, J Vessby, A Gummesson, K Heurling, A Frödén Löwenmark, O Eriksson, C Roberts, L Johansson, A Hedström, J Hulthe, C Schultheis, C Schoelch, H Niessen, M Lubberink, A Wanders, F Rorsman and H Ahlström

Publication number: 1486

Non-invasive imaging biomarkers to detect MASH in subjects with MASLD

Authors: J Vessby, P Hockings, A Gummesson, E Johansson, K Heurling, A Frödén Löwenmark, O Eriksson, L Johansson, C Roberts, A Hedström, C Schultheis, C Schoelch, H Niessen, J Hulthe, M Lubberink, H Ahlström, F Rorsman and A Wanders

Publication number: 1535

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