Fatty acid uptake using PET/MRI – today at EASD 2023

Iina Laitinen (Senior Director PET Imaging at Antaros Medical) will be sharing new data on using PET/MRI with the [18F-FTHA] radiotracer to look at change in tissue-specific fatty acid uptake (FAU) at EASD 2023. She will present the abstract today as an oral presentation as part of the session called Omics and more: unbiased approaches to tackle obesity.

Type 2 diabetes (T2D) is associated with changes in fatty acid metabolism, which can be measured as relative uptake rates in tissues. This method development study was designed to look at FAU in various tissues: skeletal muscle, subcutaneous adipose tissue (SAT), visceral adipose tissue (VAT), myocardium, liver, and brain, in both the fasted state and after a meal (also referred to as postprandially). The Positron Emission Tomography (PET) / Magnetic Resonance Imaging (MRI) method has potential to provide insights in understanding fatty acid fluxes at the multi-organ level.

The abstract is being presented on behalf of a collaboration between Eli Lily and Company, Turku PET Centre, Clinical Research Services Turku – CRST Oy, and Antaros Medical.

Title: Whole-body measurement of fatty acid uptake in fasting and postprandial conditions
Abstract number: 207
Authors: Laitinen I, Ekström S, Haraldsson H, Pierrou S, Kalliokoski K, Kiugel M, Scheinin M, Southekal S, Lu M, Coskun T, Milicevic Z, Johansson L, Nuutila P
Session: OP 35 – Omics and more: unbiased approaches to tackle obesity
Oral presentation Thursday, October 5 11:15 – 11:30 CEST

Also at EASD today, Lars Johansson (CSO at Antaros Medical) presents as part of the symposium Image-In’ what non-invasive techniques can do for diabetes research and care. You can read more about his presentation here.

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