Insulinoma is the most common form of pancreatic endocrine tumors responsible for hyperinsulinism in adults. This study show that [(68)Ga]Ga-DO3A-VS-Cys(40)-Exendin-4 has high affinity and specificity for GLP-1R expressed on insulinoma in vitro and in vivo.
Selvaraju RK, Velikyan I, Asplund V, Johansson L, Wu Z, Todorov I, Shively J, Kandeel F, Eriksson B, Korsgren O, Eriksson O
Pre-clinical Evaluation of [68Ga]Ga-DO3A-VS-Cys40-Exendin-4 For Imaging of Insulinoma.
Nucl Med Biol. 2014;41:471-6